Exposure to pesticides and digestive system cancers: systematic review and meta-analysis

Pesticides are substances often described as carcinogenic initiators for some neoplasms, such lympho-hematopoietic and breast cancer. As cancer of the digestive system, this relationship is still poorly explored requires more evidence. A systematic review with meta-analysis was conducted on association between pesticides system in PUBMED database. Of 567 papers found, 32 were approved qualitative analysis seven meta-analysis. Hexachlorobenzene DDT significantly associated colorectal (MD: 15.92; CI: 6.45; 25.40) continuous data showed a borderline binary (OR: 1.17; 0.93; 1.47). The cyclodienes family similar results both analyzes. Polychlorinated biphenyls low dosages also 38.95; 12.78; 65.11). Organophosphates 0.54; 95% 0.29; 0.98), carbamates 0.96; 0.77; 1.21) triazines 0.91; 0.74; 1.13) inconclusive results. This presents positive evidence However, required to determine role development other cancers system.